Maddy E Carelock

About Maddy E Carelock

I am currently working as a postdoctoral associate at the University of Florida under the co-mentorship of Drs. Weizhou Zhang and Elias Sayour. My research interests are primarily, but not limited to, drug development and translational immuno-oncology. I have expertise in PROTAC degrader technology and combinatorial immunotherapy approaches for multiple cancer models including pancreatic and breast cancer. My current post-doc work focuses on continued drug optimization of our newly patented PROTACs while beginning new projects involving fate mapping circulating tumor cells through machine-learning approaches. I will also be working on expanding our lab’s mRNA cancer vaccine toolbox by treating squamous cell carcinomas in aquatic large animal models such as dolphins and sea turtles.

I am involved in numerous programs throughout campus including educational initiatives such as our UFHCC Ambassador Committee and our high school and undergraduate mentorship programs such as the Student Science Training Program and University Scholars Program, respectively.

See my CV for more detailed information regarding my presentations, grants, and lab experience. Feel free to reach out regarding any questions or potential collaborations! 🙂

Accomplishments

Established UFCOM’s 1st PhD White Coat Ceremony

2024 UF College of Medicine Graduate Program
Predoctoral Award

2024 UF Health Cancer Center
PhD Candidacy

2023 UF College of Medicine Graduate Program
Predoctoral Fellow

2023 UF Health Cancer Center
Grinter Scholar

2021-2024 UF College of Medicine Graduate Program
UFHCC Ambassadorship

2021-2024 UF Health Cancer Center

Publications

Academic Articles

PROTAC-mediated NR4A1 degradation as a novel strategy for cancer immunotherapy.
2024

Journal

The Journal of experimental medicine.

Volume/Issue

221(3)

[DOI]

10.1084/jem.20231519.

[PMID]

38334978.

15 citations PubMed Publisher’s Site
Targeting intracellular proteins with cell type-specific functions for cancer immunotherapy
2023

Journal

Life Medicine.

Volume/Issue

2(3)

[DOI]

10.1093/lifemedi/lnad019.

Publisher’s Site
Breast Cancer Stem Cells: Signaling Pathways, Cellular Interactions, and Therapeutic Implications
2022

Journal

Cancers.

Volume/Issue

14(13)

[DOI]

10.3390/cancers14133287.

[PMID]

35805056.

27 citations PubMed Publisher’s Site

Education

Postdoctoral Associate

2026 University of Florida
PhD Graduate Student

2021-2025 University of Florida College of Medicine
Bachelor of Science in Biology. Concentration: Molecular Biology

2017-2021 University of South Carolina Aiken

Contact Details

Phones:

Business:: (352) 273-9000

Emails:

Business:: madison.carelock@ufl.edu

Addresses: